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2026年
发表时间杂志文章名称IF影响影子物种/组织类型测序类型测序名称
2026年5月22日Cancer Immunology, ImmunotherapyTGF-β inhibition enhances anti-tumor immunity and sensitizes PD-1 blockade therapy of bone marrow-derived myofibroblasts-induced “immunotherapy resistance” tumor model5.1成纤维细胞/免疫疗法转录组测序
mRNA测序
2026年5月25日Vita(西湖大学)Simian-specific SAGE1 enhances germline genome stability by promoting homologous recombination/小鼠/DNA损伤应答单细胞&空转测序
单细胞转录组(10x GEM-X)
2026年5月7日Advanced ScienceTargeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor-Associated Macrophages and Potentiates Antitumor Immunity14.1小鼠/巨噬细胞/结直肠癌单细胞&空转测序
单细胞测序(华大C4)
2026年3月17日Nature CommunicationsInhibition of the cancer stem cell immune checkpoint SOAT1 suppresses regulatory T cell functions through a trans-cellular 20(S)-Hydroxycholesterol-GPR132 pathway in mice15.7小鼠/肿瘤免疫逃逸转录组测序
mRNA测序
2026年4月24日Materials Today BioBioenergetic-active hybrid nanovesicles empower tumor associated macrophages phagocytosis for cancer immunotherapy10.2巨噬细胞;纳米囊泡转录组测序
mRNA测序
2026年5月1日eBioMedicineThe AGPS regulatory variant rs113671272 confers esophageal squamous cell carcinoma susceptibility through allele-specific MEIS3 binding and NF-κB activation in Chinese populations10.8细胞;食管鳞状细胞癌转录组测序
mRNA测序
2025年11月27日Clinical EpigeneticsDecoding epigenetic and transcriptional landscapes: DNA methylome-transcriptome integration reveals novel drivers in 4NQO-Induced esophageal squamous cell carcinoma mouse model4.4小鼠;食管鳞状细胞癌;肿瘤免疫微环境转录组测序
基因芯片
小鼠甲基化芯片;mRNA-seq
2026年3月20日cell death & diseaseAdipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis7.0胰腺导管腺癌;靶向免疫治疗转录组测序
表观&互作组测序
ATAC测序;mRNA测序

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